Protein Details: Gap junction alpha-5 protein

Protein ID

ICDB_Pro_0739

Protein Name

Gap junction alpha-5 protein

Gene Name

Gja5; Cxn-40

Organism

Mus musculus (Mouse)

Length

358 amino acids

AlphaFoldDB

AF-Q01231-F1-model_v4.pdb

Function

Sequence

MGDWSFLGEFLEEVHKHSTVIGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKQKLRDAEKAKEAHRTGAYEYPVAEKAELSCWKEVDGKIVLQGTLLNTYVCTILIRTTMEVAFIVGQYLLYGIFLDTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMMAVAGLSLFLSLAELYHLGWKKIRQRFGKSRQGVDKHQLPGPPTSLVQSLTPPPDFNQCLKNSSGEKFFSDFSNNMGSRKNPDALATGEVPNQEQIPGEGFIHMHYSQKPEYASGASAGHRLPQGYHSDKRRLSKASSKARSDDLSV

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Abundantly expressed in the lung; also expressed in the kidney and heart

DOI ID

10.1083/jcb.117.6.1299; 10.1101/gr.2596504; 10.1161/circresaha.116.308825

RefSeq

NP_001258557.1; NP_032147.1